Promethazine HCl and codeine phosphate oral Answer is not proposed to be used in pregnant Girls [see Use in Precise Populations (eight.1)]. Extended usage of promethazine HCl and codeine phosphate oral Option during pregnancy may end up in neonatal opioid withdrawal syndrome, which may be lifetime-threatening if not regarded and dealt with, and requires management As outlined by protocols created by neonatology specialists.
A family teaspoon is just not an accurate measuring machine and may lead to overdosage [see Warnings and Safeguards (five.seven)]. For prescriptions where a measuring machine isn't delivered, a pharmacist can provide an ideal measuring device and can provide Guidelines for measuring the right dose. Never overfill. Rinse the measuring gadget with drinking water right after Each individual use.
Promoting or freely giving Promethazine with Codeine Oral Option might damage Other individuals, which is in opposition to the legislation. Tell your healthcare company For those who have ever abused or been depending on Alcoholic beverages, prescription medicines or street medicine. Promethazine with Codeine Oral Resolution is just not for youngsters below six a long time of age.
Promethazine is very well absorbed in the gastrointestinal tract. Scientific outcomes are obvious within twenty minutes right after oral administration and generally final 4 to 6 hours, While They could persist provided that twelve hours.
Drug interactions may change how your drugs do the job or enhance your hazard for major Unwanted effects. This document isn't going to incorporate get more info all attainable drug interactions.
Usually do not enhance your dose or use this solution far more generally or for longer than prescribed. Your condition won't improve any a lot quicker, and also your possibility of Unintended effects will raise.
For the reason that fish scale cocaine can be a purer sort of the drug that doesn’t have as quite a few additives, or adulterants, combined in, it really is costlier than the typical cocaine offered on the streets.
Lean gets its identify within the influence it's on people that drink it: they tend to slouch or lean to at least one aspect the more they eat the substance. The results of codeine are like These of other addictive opioids (such as oxycodone and heroin).
In the event the response to an opioid antagonist is suboptimal or only transient in character, administer more antagonist as directed because of the product or service’s prescribing information and facts. The respiratory depressant consequences of promethazine are not reversed by opioid antagonists, like naloxone.
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Use with warning; start with decrease doses or with lengthier dosing intervals and titrate slowly but surely although diligently monitoring for Unintended effects.
This is simply not a whole listing of probable Unintended effects. For those who detect other Unintended effects not outlined above, contact your health care provider or pharmacist.
Promethazine is metabolized from the liver to a range of inactive metabolites like sulfoxides of promethazine, N-demethylpromethazine together with other glucuronides.
In a few little ones and Older people this occurs very quickly, and can result in you to halt respiratory and cause death as a result of an overdose.